Postdoctoral position: Gene expression regulation (f/m/d) Wiss2603-13

Faculty of Mathematics and Natural Sciences

Postdoctoral position: Gene expression regulation (f/m/x)

Uhlirova Lab/Institute for Genetics/CECAD

We are one of the largest and oldest universities in Europe and one of the most important employers in our region.

Our broad range of subjects, the dynamic development of our main research areas and our central location in Cologne

make us attractive for students and researchers from around the world. We offer a wide range of career opportunities in

science, technology, and administration.

The Uhlirova lab (www.uni-koeln.de/inter-fak/cecad/uhlirova/) explores how stress-indu- WE OFFER

cible signaling pathways control gene expression and influence tissue homeostasis and » Interactive and international team with access to the state-of -the-art research

longevity. To tackle these questions, we combine the power of functional genetics in facilities

Drosophila and mouse models with cutting-edge molecular and cell biology, multi-omics » A diverse working environment with equal opportunities

approaches, advanced microscopy, and bioinformatics. We are looking for a highly moti- » Support in balancing work and family life

vated and curious postdoctoral candidate (f/m/x) to join our dynamic team. You will have

» Extensive advanced training opportunities

the opportunity to lead your own project, contribute to collaborative research, and develop

» Occupational health management offers

skills at the interface of genetics, molecular and cell biology, and systems-level analysis.

» Flexible working time models

YOUR TASKS The University of Cologne promotes equal opportunities and diversity. Women will be con-

» To study the crosstalk between transcription and pre-mRNA splicing under physio- sidered preferentially in accordance with the Equal Opportunities Act of North Rhine-Westphalia (Landesgleichstellungsgesetz – LGG NRW). We also expressly welcome applications

logical, stress, and disease conditions

from all suitable candidates regardless of their gender, nationality, ethnic and social origin,

» To investigate mechanisms underlying spliceosome assembly and functional plasticity

religion, disability, age, sexual orientation and identity.

» To uncover what renders different transcripts, cells, and tissues sensitive to aberrant

splicing

The position is available from 1 October 2026 on a full-time basis (39,83 hours per

» To elucidate how spliceosome malfunction impacts genome stability and contributes

week). It is limited for two years until 30 September 2028. If the applicant meets the

to loss of tissue homeostasis, premature ageing and diseases

relevant wage requirements and personal qualifications, the salary is based on remune-

YOUR PROFILE ration group 13 TV-L of the pay scale for the German public sector.

» Completed doctoral degree in Biology / Biochemistry/ Biophysics or related areas of

Life Sciences Please apply online with proof of the required qualifications and the following documents:

» Motivation, curiosity and creativity, and a strong ability to solve problems through

critical analytical thinking » A cover letter describing your motivation to join our research group and information

» Strong background in genetics, molecular and cell biology is essential on your career achievements (1 page max.)

» Proven ability to carry out an independent scientific project and unwavering commit- » Academic Curriculum Vitae (without a photo), including your publication list and

ment to high-quality research contact information for three references

» Hands-on experience in working with model organisms, preferably Drosophila and/or » Copies of your degree and qualification certificate

mouse and in vitro systems Please apply at: https://jobportal.uni-koeln.de. The reference number is Wiss2603-13.

» Excellent communication skills, fluency in spoken and written English The application deadline is 15 June 2026. For further inquiries, please contact Professor

» Strong commitment to collaboration and teamwork Mirka Uhlirova/Dr Esther Wollert at (uhlirova-jobs@uni-koeln.de) and take a look at our

FAQs.

Desired Assets

» Experience in multi-omics research projects and data analysis

» Familiarity with iPSC and / or organoid models

» Expertise in computational modeling of protein–RNA and protein–protein interactions

» Experience in quantitative image analysis and attention to detail

» Strong organizational and thorough documentation skills