PhD Position in Redox Chemical Biology

PhD Position in Redox Chemical Biology

Über die Stelle

The University of Zurich, Switzerland’s largest university, offers a range of attractive positions in various subject areas and professional fields. With around 10,000 employees and currently 12 professional apprenticeship streams the University offers an inspiring working environment on cutting-edge research and top-class education. Put your talent and skills to work with us. Find out more about UZH as an employer!

Aufgaben

As a PhD student working on any of these projects, you would model protein-based fluorescent sensors using the latest artificial intelligence algorithms. You would clone, express and purify proteins, and characterize them spectroscopically and structurally by various techniques, including X-ray crystallography. You would also clone vectors for expression in mammalian cells to enable live-cell imaging experiments. In all cases, you would be expected to use state-of-the-art data analysis methods, including machine learning, to gain insight from your observations. Later in the project, you would work collaboratively to develop stable cell lines using genome editing techniques and contribute to a large knock-out screening campaign. This position involves very little to no synthetic organic chemistry. Additionally, you would be an active member of our group, contributing to routine lab maintenance, participating in group meetings and in selected outreach activities. You would also contribute to teaching as assistant in lab courses and lectures. You would also write reports and papers, and prepare presentations for national and international conferences.

Anforderungen

Highly motivated student with a solid background in molecular biology or biochemistry. A background in synthetic organic, inorganic or materials chemistry, engineering, or theoretical chemistry, with no experience in molecular biology, cell biology, or biochemistry is not suitable for this position. Strongly interested in developing new technologies to visualize proteins in complex biological samples and elucidate mechanisms in redox biology. Previous experience in de novo protein design, directed evolution, redox biology, bioinformatics and/or machine learning is an advantage. MSc degree in chemistry, biochemistry, molecular biology, or bioengineering and proficiency in oral and written English are formal requirements.

Ausbildung

University

Benefits

Our employees benefit from a wide range of attractive offers. More